A PPY cDNA clone identifies a frequent RFLP.

Human cDNA probe detects RFLP on chromosome 12, OL 202 (HGM8 designated no. D12S9).

SOURCE AND DESCRIPTION OF CLONE: 0.6 kb anonymous lymphocyte cDNA cloned into the PstI site of pUR291. POLYMORPHISM: Bglll identifies a two allele polymorphism with a band at either 5.2 kb (A 1) or 5.0 kb (A 2) and invariant bands at approximately

RFLP detected by an X-linked cDNA encoding erythroid-potentiating activity/tissue inhibitor of metalloproteinase (EPA/TIMP).

SOURCE/DESCRIPTION: A full length (1.1 kb) human EPA cDNA * clone inserted in p91023(B) at the EcoRI restriction site * (1). POLYMORPHISM: Bglll identifies a two allele polymorphism with • bands of approximately 12 kb (Al) or 9.5 and 2.5-kb (A2). « t FREQUENCY: A total of 102 X chromosomes from 54 unrelated individuals was examined. £ Al (12 kb allele): 0.66 PvuII or Xbal with a panel of three ...

RFLP for a gene-related sequence of alpha 1-antitrypsin (AAT).

SOURCE/DESCRIPTION : A cDNA clone containing a 250 bp insert of the AAT gene (Rogers et al., 1983).

RFLP for Duchenne muscular dystrophy cDNA clone 44-1.

Cloning of Ly-5 cDNA.

A notable feature of Ly-5, among immunogenetic systems that identify glycoproteins of the cell surface and define the surface phenotype of cells according to their lineage, is that the Ly-5 locus specifies a range of molecular isoforms that distinguish cells of different stages and branches of hematopoietic development. The composition of the Ly-5 locus is of much interest in regard to how thes...